Hemichorea in the Setting of Diabetic Striatopathy Uniquely Associated with Concurrent Myelofibrosis: A Case Report

Isabella Chesca P. Tayag, Raymond L. Rosales

Apr 2026 DOI 10.35460/2546-1621.2025-0205     Access   

Abstract

Hemichorea, a hyperkinetic disorder characterized by involuntary, rapid, irregular movements on one side of the body, typically originates from cortical basal ganglia involvement, particularly the striatum. We present a 63-year-old Filipino female with poor glycemic control and known idiopathic myelofibrosis exhibiting chorea-ballism movements in the right distal and proximal extremities. Significant improvement in involuntary movements was observed upon optimal glycemic control and benzodiazepine therapy. This report underscores the noteworthy presentation of uncontrolled hyperglycemia in type 2 diabetes, while highlighting the potential contribution of myelofibrosis.

Key words: Diabetic Striatopathy, Myelofibrosis

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