Time to Ride the Wave of Precision Medicine
Raymond L. Rosales
April 2019 DOI 10.35460/2546-1621.v3i1-editorial Access
Journal for Medicine, UST
Editor: Dr. Raymond Rosales
ISSN: 2546-1621
Volume 3 Issue 1
In this third issue of JMUST, we have fully implemented our digital authoring platform and by using a dedicated electronic, publicly-accessible platform, we have joined the ranks of many established international scientific and medical journals.
We welcome all our readers to JMUST’s 10 articles: 5 of them are clinical or observational studies, 2 are case reports, 1 meta-analysis, 1 qualitative research on medical students, 1 on medical education, and this editorial.
Raymond L. Rosales
April 2019 DOI 10.35460/2546-1621.v3i1-editorial Access
Elizabeth Aileen Garan-Giller, Dominico Carlo S. Dator, Mart Blas Angelo P. Juan, Genevieve Anne R. Querubin, Tiphanie P. Sevilla, Maria Minerva P. Calimag
April 2019 DOI 10.35460/2546-1621.2019-0001 Access
A vast majority of research on academic stress is centered on its contributing factors and how they affect other aspects of students’ lives. Coping mechanisms and effective ways in dealing with stress have also been delved into, but none have dwelt on a study of the medical students' lived experience of academic stress. There was no study found in literature which examined and collectively characterized the different phases that medical students go through in coping with academic stress, hence the impetus to undertake this study. Anchored on the Transactional Model of coping with stress, this study was undertaken to answer the central question: How do Filipino medical students collectively characterize the phases they undergo in coping with the stresses in medical school?
Leilani B. Mercado-Asis, Mary Jane Tanchee-Ngo, Erick S. Mendoza, Gaurav Puppalwar, Ashish Mane, Anand Vasam, Agam Shah, Rishi Jain
April 2019 DOI 10.35460/2546-1621.2019-0010 Access
The high prevalence of type 2 diabetes mellitus (T2DM) in Philippines has burdened the health care system. Therefore, we compared standard of care, Insulin30/70+ Insulin Glulisine (Arm B) to a traditional insulin regimen NPH Insulin+Regular Insulin (Arm A) to test the concept that both provide comparable efficacy and safety in real world practice.
Gabriel Alfonso B. Javier, Alberto Ma. V. Molano
April 2019 DOI 10.35460/2546-1621.2018-0056 Access
Anterior Cruciate Ligament (ACL) reconstruction is commonly performed to restore knee kinematics and halt the progression of osteoarthritis. A primary variable that could influence the outcome of ACL reconstruction is the tension applied to the graft at the time of fixation. If the tension is too great, an abnormal compressive force could potentially develop across the tibiofemoral joint, hindering knee motion, and subjecting the articular surfaces to increased stress. If the tension in the graft is too low, the graft will not be effective in restoring normal kinematics. The Tegner Lysholm Knee Scale is a functional scoring for patients with ligamentous injuries. It is a patient-reported measure of knee function and is important for comprehensive assessment conditions in both the clinical and research context. Our objective was to compare which tension technique (15 lbs graft tension using a Mitek Tensioner™ vs maximal sustained two-hand technique) would yield better functional outcome at 6 months and 12 months postoperatively using the Tegner Lysholm Knee Scale.
Donaryn Pasamonte, Flordeluna Z. Mesina
April 2019 DOI 10.35460/2546-1621.2018-0021 Access
Multiple myeloma (MM) causes generalized bone loss leading to lytic bone lesions and pathologic fractures. The increased osteoclast activity and reduced osteoblast function favors bone resorption and decrease bone formation. Vitamin D is vital in regulating calcium homeostasis and osteoclast-mediated bone resorption. Deficiency of Vitamin D among MM patients may complicate bone mineralization problems and fractures.
Joanna Luisa Z. Salvador, Angelita T. Garcia, Flordeluna Z. Mesina,
April 2019 DOI 10.35460/2546-1621.2018-0052 Access
Monoclonal antibodies have revolutionized the treatment of immune-mediated inflammatory diseases (eg, rheumatoid arthritis [RA], Crohn's disease [CD], and psoriasis) as well as malignant diseases. Currently, there are about 100 monoclonal antibodies and even more are expected in the coming years. Knowledge of not only their mechanism of action but also their adverse event profile is tantamount. One of the distinctive side effects of these drugs is the potential for non-allergic and allergic infusion reactions caused by cytokine release. These adverse reactions should be monitored and managed immediately for patient welfare and safety.
Gelinemae G. Malaza, Elaine C. Cunanan
April 2019 DOI 10.35460/2546-1621.2018-0020 Access
Maternal hyperglycemia during the peripartum period is highly correlated with fetal hyperinsulinemia and consequent neonatal hypoglycemia. Liberal use of intravenous glucose therapy prior to delivery can potentially cause maternal hyperglycemia, therefore, it is prudent to implement all preventive measures.
This study aims to determine the occurrence of neonatal hypoglycemia with intravenous glucose therapy prior to delivery in maternal diabetes mellitus.
Patrick Henry Lorenzo, Jeremy James C. Munji
April 2019 DOI 10.35460/2546-1621.2018-0047 Access
Ma. Felisse Carmen Gomez, Florence Rochelle Gan, Erick Mendoza, Leilani B. Mercado Asis
April 2019 DOI 10.35460/2546-1621.2018-0055 Access
Unilateral adrenalectomy has not been recommended in the guidelines as a treatment for primary hyperaldosteronism secondary to bilateral adrenal hyperplasia (BAH). Interestingly, recent studies have shown that increased circulation of aldosterone increased oxidative stress, cardiovascular (CV) complications such as atrial fibrillation, myocardial infarction and heart failure; and that unilateral adrenalectomy led to improved CV function. Therefore, recognizing the role of unilateral adrenalectomy in BAH, specifically for improved quality of life is important.
Mika Ana S. Frio, Sandra V. Navarra
April 2019 DOI 10.35460/2546-1621.2018-0042 Access
Leilani B. Mercado-Asis
April 2019 DOI 10.35460/2546-1621.2019-0023 Access
Part 2 of TOCSE is geared towards 3rd year medical students preparing to be in the 4th year. It has the following important elements as follows: